the accuracy of sentinel lymph node biopsy compared with axillary lymph node dissection in breast cancer
نویسندگان
چکیده
background : sentinel lymph node biopsy is used as an accurate staging procedure to detect early breast cancer. several studies have documented that sentinel lymph node biopsy can accurately determine the status of axillary nodes. sentinel node biopsy offers the advantage of accurately staging the axilla and eliminating the need for a full axillary dissection for patients who have a negative sentinel node. the aim of this study is to determine the predictors of non-sentinel lymph node metastasis by sentinel node biopsy. methods : in this study, all patients (n=88) who underwent sentinel node biopsy for invasive breast cancer from june 2005 to june 2010 in shahid faghihi hospital, shiraz, iran were enrolled. we reviewed the medical files of patients and their tumor characteristics. statistical analysis was performed to determine whether any of these characteristics alone could accurately predict the remaining non-sentinel node status. spss statistical package was used. results : the mean age of the patients was 46.1 years. tumor size was 2.73 cm. of the 88 patients who underwent complete axillary node dissection, 34 had metastases in the non-sentinel nodes, with a mean of 4 positive non-sentinel nodes in each patient. statistically, neither the patient’s age nor the clinicopathological features of the tumor were significantly associated with non-sentinel node metastases (all: p>0.05). conclusion : our study shows that neither the primary tumor characteristics nor the size of metastasis in the sentinel lymph node can predict the status of non-sentinel nodes. however, further investigation is necessary. complete axillary node dissection should remain the most appropriate management for patients with positive sentinel lymph nodes.
منابع مشابه
Axillary Lymph Node Dissection in Breast Cancer Patients. the Role of Sentinel Lymph Node Biopsy
Rationale. Since its introduction in the early 1990s, sentinel lymph node biopsy (SLNB) is regarded as the standard treatment for patients with clinically negative axillary lymph nodes (LNs) on initial presentation. Classically, when the SLN biopsy is negative, the axillary LN dissection (ALND) is no further necessary. On the other hand, performing complete ALND in case of a positive SLNB is co...
متن کاملArm lymphoscintigraphy after axillary lymph node dissection or sentinel lymph node biopsy in breast cancer
PURPOSE Compare the lymphatic flow in the arm after breast cancer surgery and axillary lymph node dissection (ALND) versus sentinel lymph node biopsy (SLNB) using lymphos-cintigraphy (LS). PATIENTS AND METHODS A cross-sectional study with 39 women >18 years who underwent surgical treatment for unilateral breast cancer and manipulation of the axillary lymph node chain through either ALND or SL...
متن کاملMorbidity following sentinel lymph node biopsy versus axillary lymph node dissection for patients with breast carcinoma.
BACKGROUND Axillary lymph node dissection for staging the axilla in breast carcinoma patients is associated with considerable morbidity, such as edema of the arm, pain, sensory disturbances, impairment of arm mobility, and shoulder stiffness. Sentinel lymph node biopsy electively removes the first lymph node, which gets the drainage from the tumor and should therefore be associated with nearly ...
متن کاملRadiation exposure of the surgeons in sentinel lymph node biopsy
Background: Sentinel node biopsy (SLNB) is the standard of care for breast cancer treatment and it is getting wide acceptance in Iran. The radiation safety of the procedure has been investigated under controlled conditions, but the standard dose of radiotracer and techniques are not always observed in the community setting. The aim of this study was to assess the magnitude of the absor...
متن کاملDissection axillary lymph node count in patient with breast cancer followed by neoadjuvant therapy
Introduction: Breast cancer is the most common cancer and the second cause of death in women. It is essential to have the highest level of confidence in axillary staging assessment. Many surgeons and pathologists believe that fewer lymph nodes are present in axillary dissection specimens of women treated by neoadjuvant chemotherapy. Consequently, the purpose of this study was to compare the lym...
متن کاملمنابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
middle east journal of cancerجلد ۲، شماره ۳ & ۴، صفحات ۹۹-۰
میزبانی شده توسط پلتفرم ابری doprax.com
copyright © 2015-2023